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A Genetic Selection for dinB Mutants Reveals an Interaction between DNA Polymerase IV and the Replicative Polymerase That Is Required for Translesion Synthesis

Translesion DNA synthesis (TLS) by specialized DNA polymerases (Pols) is a conserved mechanism for tolerating replication blocking DNA lesions. The actions of TLS Pols are managed in part by ring-shaped sliding clamp proteins. In addition to catalyzing TLS, altered expression of TLS Pols impedes cel...

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Detalles Bibliográficos
Autores principales:	Scotland, Michelle K., Heltzel, Justin M. H., Kath, James E., Choi, Jung-Suk, Berdis, Anthony J., Loparo, Joseph J., Sutton, Mark D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564189/ https://www.ncbi.nlm.nih.gov/pubmed/26352807 http://dx.doi.org/10.1371/journal.pgen.1005507

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