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A Gene Gravity Model for the Evolution of Cancer Genomes: A Study of 3,000 Cancer Genomes across 9 Cancer Types

Cancer development and progression result from somatic evolution by an accumulation of genomic alterations. The effects of those alterations on the fitness of somatic cells lead to evolutionary adaptations such as increased cell proliferation, angiogenesis, and altered anticancer drug responses. How...

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Detalles Bibliográficos
Autores principales:	Cheng, Feixiong, Liu, Chuang, Lin, Chen-Ching, Zhao, Junfei, Jia, Peilin, Li, Wen-Hsiung, Zhao, Zhongming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564226/ https://www.ncbi.nlm.nih.gov/pubmed/26352260 http://dx.doi.org/10.1371/journal.pcbi.1004497

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