Intrahepatic Transcriptional Signature Associated with Response to Interferon-α Treatment in the Woodchuck Model of Chronic Hepatitis B

Recombinant interferon-alpha (IFN-α) is an approved therapy for chronic hepatitis B (CHB), but the molecular basis of treatment response remains to be determined. The woodchuck model of chronic hepatitis B virus (HBV) infection displays many characteristics of human disease and has been extensively...

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Detalles Bibliográficos
Autores principales: Fletcher, Simon P., Chin, Daniel J., Gruenbaum, Lore, Bitter, Hans, Rasmussen, Erik, Ravindran, Palanikumar, Swinney, David C., Birzele, Fabian, Schmucki, Roland, Lorenz, Stefan H., Kopetzki, Erhard, Carter, Jade, Triyatni, Miriam, Thampi, Linta M., Yang, Junming, AlDeghaither, Dalal, Murredu, Marta G., Cote, Paul, Menne, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564242/
https://www.ncbi.nlm.nih.gov/pubmed/26352406
http://dx.doi.org/10.1371/journal.ppat.1005103

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