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Altered distribution of I(Ca) impairs Ca release at the t-tubules of ventricular myocytes from failing hearts
In mammalian cardiac ventricular myocytes, Ca influx and release occur predominantly at t-tubules, ensuring synchronous Ca release throughout the cell. Heart failure is associated with disrupted t-tubule structure, but its effect on t-tubule function is less clear. We therefore investigated Ca influ...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Academic Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564288/ https://www.ncbi.nlm.nih.gov/pubmed/26103619 http://dx.doi.org/10.1016/j.yjmcc.2015.06.012 |