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Reactivation of CDX2 in Gastric Cancer as Mark for Gene Silencing Memory

To explore the epigenetic mechanism that reactivates CDX2 (a homeobox transcription factor that serves as a tumor-suppressor gene) in intestinal-type gastric cancer during cancer progression, we examined the methylation status of the CDX2 gene promoter and the expression pattern of methyl-CpG bindin...

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Detalles Bibliográficos
Autores principales: Kameoka, Yuri, Kitazawa, Riko, Ariasu, Kanazu, Tachibana, Ryosuke, Mizuno, Yosuke, Haraguchi, Ryuma, Kitazawa, Sohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564377/
https://www.ncbi.nlm.nih.gov/pubmed/26379313
http://dx.doi.org/10.1267/ahc.15014