Vaccination With a Highly Attenuated Recombinant Vesicular Stomatitis Virus Vector Protects Against Challenge With a Lethal Dose of Ebola Virus

Previously, recombinant vesicular stomatitis virus (rVSV) pseudotypes expressing Ebolavirus glycoproteins (GPs) in place of the VSV G protein demonstrated protection of nonhuman primates from lethal homologous Ebolavirus challenge. Those pseudotype vectors contained no additional attenuating mutatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Matassov, Demetrius, Marzi, Andrea, Latham, Terri, Xu, Rong, Ota-Setlik, Ayuko, Feldmann, Friederike, Geisbert, Joan B., Mire, Chad E., Hamm, Stefan, Nowak, Becky, Egan, Michael A., Geisbert, Thomas W., Eldridge, John H., Feldmann, Heinz, Clarke, David K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Infectious Diseases Society of America 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564554/
https://www.ncbi.nlm.nih.gov/pubmed/26109675
http://dx.doi.org/10.1093/infdis/jiv316

Ejemplares similares

Ejemplares similares