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Epigenomics of Neural Cells: REST-Induced Down- and Upregulation of Gene Expression in a Two-Clone PC12 Cell Model
Cell epigenomics depends on the marks released by transcription factors operating via the assembly of complexes that induce focal changes of DNA and histone structure. Among these factors is REST, a repressor that, via its strong decrease, governs both neuronal and neural cell differentiation and sp...
Autores principales: | Garcia-Manteiga, Jose M., Bonfiglio, Silvia, Malosio, Maria Luisa, Lazarevic, Dejan, Stupka, Elia, Cittaro, Davide, Meldolesi, Jacopo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564578/ https://www.ncbi.nlm.nih.gov/pubmed/26413508 http://dx.doi.org/10.1155/2015/202914 |
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