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Epigenomics of Neural Cells: REST-Induced Down- and Upregulation of Gene Expression in a Two-Clone PC12 Cell Model

Cell epigenomics depends on the marks released by transcription factors operating via the assembly of complexes that induce focal changes of DNA and histone structure. Among these factors is REST, a repressor that, via its strong decrease, governs both neuronal and neural cell differentiation and sp...

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Detalles Bibliográficos
Autores principales: Garcia-Manteiga, Jose M., Bonfiglio, Silvia, Malosio, Maria Luisa, Lazarevic, Dejan, Stupka, Elia, Cittaro, Davide, Meldolesi, Jacopo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564578/
https://www.ncbi.nlm.nih.gov/pubmed/26413508
http://dx.doi.org/10.1155/2015/202914

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