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Facile Discovery of a Diverse Panel of Anti-Ebola Virus Antibodies by Immune Repertoire Mining
The ongoing evolution of Ebolaviruses poses significant challenges to the development of immunodiagnostics for detecting emergent viral variants. There is a critical need for the discovery of monoclonal antibodies with distinct affinities and specificities for different Ebolaviruses. We developed an...
Autores principales: | Wang, Bo, Kluwe, Christien A., Lungu, Oana I., DeKosky, Brandon J., Kerr, Scott A., Johnson, Erik L., Jung, Jiwon, Rezigh, Alec B., Carroll, Sean M., Reyes, Ann N., Bentz, Janelle R., Villanueva, Itamar, Altman, Amy L., Davey, Robert A., Ellington, Andrew D., Georgiou, George |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564727/ https://www.ncbi.nlm.nih.gov/pubmed/26355042 http://dx.doi.org/10.1038/srep13926 |
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