Ion channels gated by acetylcholine and serotonin: structures, biology, and drug discovery

The nicotinic acetylcholine receptors (nAChRs) and the 5-HT(3) receptors (5-HT(3)Rs) are cation-selective members of the pentameric ligand-gated ion channels (pLGICs), which are oligomeric protein assemblies that convert a chemical signal into an ion flux through postsynaptic membrane. They are crit...

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Detalles Bibliográficos
Autores principales: Wu, Zhong-shan, Cheng, Hao, Jiang, Yi, Melcher, Karsten, Xu, H Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564887/
https://www.ncbi.nlm.nih.gov/pubmed/26238288
http://dx.doi.org/10.1038/aps.2015.66

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564887/
https://www.ncbi.nlm.nih.gov/pubmed/26238288
http://dx.doi.org/10.1038/aps.2015.66

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