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Protracted dormancy of pre-leukemic stem cells
Cancer stem cells can escape therapeutic killing by adopting a quiescent or dormant state. The reversibility of this condition provides the potential for later recurrence or relapse, potentially many years later. We describe the genomics of a rare case of childhood BCR-ABL1-positive, B-cell precurso...
Autores principales: | Ford, A M, Mansur, M B, Furness, C L, van Delft, F W, Okamura, J, Suzuki, T, Kobayashi, H, Kaneko, Y, Greaves, M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564945/ https://www.ncbi.nlm.nih.gov/pubmed/26017033 http://dx.doi.org/10.1038/leu.2015.132 |
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