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Respiration and substrate transport rates as well as reactive oxygen species production distinguish mitochondria from brain and liver

BACKGROUND: Aberrant mitochondrial function, including excessive reactive oxygen species (ROS) production, has been implicated in the pathogenesis of human diseases. The use of mitochondrial inhibitors to ascertain the sites in the electron transport chain (ETC) resulting in altered ROS production c...

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Detalles Bibliográficos
Autores principales: Gusdon, Aaron M., Fernandez-Bueno, Gabriel A., Wohlgemuth, Stephanie, Fernandez, Jenelle, Chen, Jing, Mathews, Clayton E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564979/
https://www.ncbi.nlm.nih.gov/pubmed/26358560
http://dx.doi.org/10.1186/s12858-015-0051-8

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