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Respiration and substrate transport rates as well as reactive oxygen species production distinguish mitochondria from brain and liver
BACKGROUND: Aberrant mitochondrial function, including excessive reactive oxygen species (ROS) production, has been implicated in the pathogenesis of human diseases. The use of mitochondrial inhibitors to ascertain the sites in the electron transport chain (ETC) resulting in altered ROS production c...
Autores principales: | Gusdon, Aaron M., Fernandez-Bueno, Gabriel A., Wohlgemuth, Stephanie, Fernandez, Jenelle, Chen, Jing, Mathews, Clayton E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564979/ https://www.ncbi.nlm.nih.gov/pubmed/26358560 http://dx.doi.org/10.1186/s12858-015-0051-8 |
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