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Increased Power for Detection of Parent-of-Origin Effects via the Use of Haplotype Estimation
Parent-of-origin (or imprinting) effects relate to the situation in which traits are influenced by the allele inherited from only one parent and the allele from the other parent has little or no effect. Given SNP genotype data from case-parent trios, the parent of origin of each allele in the offspr...
Autores principales: | Howey, Richard, Mamasoula, Chrysovalanto, Töpf, Ana, Nudel, Ron, Goodship, Judith A., Keavney, Bernard D., Cordell, Heather J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564992/ https://www.ncbi.nlm.nih.gov/pubmed/26320892 http://dx.doi.org/10.1016/j.ajhg.2015.07.016 |
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