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Mechanistic-enriched models: integrating transcription factor networks and metabolic deregulation in cancer
BACKGROUND: In the present paper we will examine methodological frameworks to study complex genetic diseases (e.g. cancer) from the stand point of theoretical-computational biology combining both data-driven and hypothesis driven approaches. Our work focuses in the apparent counterpoint between two...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565005/ https://www.ncbi.nlm.nih.gov/pubmed/26353769 http://dx.doi.org/10.1186/s12976-015-0012-3 |