Cargando…
Reverse engineering of logic-based differential equation models using a mixed-integer dynamic optimization approach
Motivation: Systems biology models can be used to test new hypotheses formulated on the basis of previous knowledge or new experimental data, contradictory with a previously existing model. New hypotheses often come in the shape of a set of possible regulatory mechanisms. This search is usually not...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565031/ https://www.ncbi.nlm.nih.gov/pubmed/26002881 http://dx.doi.org/10.1093/bioinformatics/btv314 |