Cargando…

Bite-to-hospital time and morbidity in victims of viper bite in a rural hospital in Nigeria

BACKGROUND: Mortality amongst in-hospital patients bitten by carpet viper in northern Nigeria has reduced, related to use of a monospecific ovine Fab snake antivenom. However, many victims survive with temporary or permanent morbidity. OBJECTIVES: Study objectives were to: (1) determine and score th...

Descripción completa

Detalles Bibliográficos
Autor principal: Ogunfowokan, Oluwagbenga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AOSIS OpenJournals 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565144/
http://dx.doi.org/10.4102/phcfm.v4i1.371
_version_ 1782389565375381504
author Ogunfowokan, Oluwagbenga
author_facet Ogunfowokan, Oluwagbenga
author_sort Ogunfowokan, Oluwagbenga
collection PubMed
description BACKGROUND: Mortality amongst in-hospital patients bitten by carpet viper in northern Nigeria has reduced, related to use of a monospecific ovine Fab snake antivenom. However, many victims survive with temporary or permanent morbidity. OBJECTIVES: Study objectives were to: (1) determine and score the morbidity caused by carpet viper bite; and (2) find the relationship between bite-to-hospital time and morbidity amongst victims of carpet viper bite. METHOD: A prospective study was conducted in a rural hospital in north-central Nigeria. The morbidities scored were oedema, tenderness, prolonged whole-blood clotting time, blister, ulcer, need for blood transfusion, coma, hypotension, convulsion, length of hospital stay, need for disarticulation, and need for skin graft. A score of one was given to each objective sign. The bite-to-hospital time of 233 subjects was obtained. Descriptive and inferential statistical analysis was done. RESULTS: Most of the subjects (150 or 64%) came to the hospital within 6 hours of the snake bite, with 2 (1%) arriving within 1 hour. The median bite-to-hospital time was 5 hours, with a range of 0.5–216 hours. Major morbidities were oedema, seen in 212 (91.0%; 95% CI 86.6–94.3%); incoagulable blood, seen in 205 (88%; 95% CI 83.1–91.9%), and tenderness, seen in 201 (86.3%; 95% CI 81.2–90.4%). The mean morbidity score was 8 ± 4. For every unit increase in logged bite-to-hospital time, the morbidity score increased by 1.85 (p < 0.001). CONCLUSION: Morbidity caused by carpet viper bite is high in Zamko, north-central Nigeria, and correlates with increasing bite-to-hospital time.
format Online
Article
Text
id pubmed-4565144
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher AOSIS OpenJournals
record_format MEDLINE/PubMed
spelling pubmed-45651442016-02-03 Bite-to-hospital time and morbidity in victims of viper bite in a rural hospital in Nigeria Ogunfowokan, Oluwagbenga Afr J Prim Health Care Fam Med Original Research BACKGROUND: Mortality amongst in-hospital patients bitten by carpet viper in northern Nigeria has reduced, related to use of a monospecific ovine Fab snake antivenom. However, many victims survive with temporary or permanent morbidity. OBJECTIVES: Study objectives were to: (1) determine and score the morbidity caused by carpet viper bite; and (2) find the relationship between bite-to-hospital time and morbidity amongst victims of carpet viper bite. METHOD: A prospective study was conducted in a rural hospital in north-central Nigeria. The morbidities scored were oedema, tenderness, prolonged whole-blood clotting time, blister, ulcer, need for blood transfusion, coma, hypotension, convulsion, length of hospital stay, need for disarticulation, and need for skin graft. A score of one was given to each objective sign. The bite-to-hospital time of 233 subjects was obtained. Descriptive and inferential statistical analysis was done. RESULTS: Most of the subjects (150 or 64%) came to the hospital within 6 hours of the snake bite, with 2 (1%) arriving within 1 hour. The median bite-to-hospital time was 5 hours, with a range of 0.5–216 hours. Major morbidities were oedema, seen in 212 (91.0%; 95% CI 86.6–94.3%); incoagulable blood, seen in 205 (88%; 95% CI 83.1–91.9%), and tenderness, seen in 201 (86.3%; 95% CI 81.2–90.4%). The mean morbidity score was 8 ± 4. For every unit increase in logged bite-to-hospital time, the morbidity score increased by 1.85 (p < 0.001). CONCLUSION: Morbidity caused by carpet viper bite is high in Zamko, north-central Nigeria, and correlates with increasing bite-to-hospital time. AOSIS OpenJournals 2012-06-13 /pmc/articles/PMC4565144/ http://dx.doi.org/10.4102/phcfm.v4i1.371 Text en © 2012. The Authors http://creativecommons.org/licenses/by/2.0/ AOSIS OpenJournals. This work is licensed under the Creative Commons Attribution License.
spellingShingle Original Research
Ogunfowokan, Oluwagbenga
Bite-to-hospital time and morbidity in victims of viper bite in a rural hospital in Nigeria
title Bite-to-hospital time and morbidity in victims of viper bite in a rural hospital in Nigeria
title_full Bite-to-hospital time and morbidity in victims of viper bite in a rural hospital in Nigeria
title_fullStr Bite-to-hospital time and morbidity in victims of viper bite in a rural hospital in Nigeria
title_full_unstemmed Bite-to-hospital time and morbidity in victims of viper bite in a rural hospital in Nigeria
title_short Bite-to-hospital time and morbidity in victims of viper bite in a rural hospital in Nigeria
title_sort bite-to-hospital time and morbidity in victims of viper bite in a rural hospital in nigeria
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565144/
http://dx.doi.org/10.4102/phcfm.v4i1.371
work_keys_str_mv AT ogunfowokanoluwagbenga bitetohospitaltimeandmorbidityinvictimsofviperbiteinaruralhospitalinnigeria