Characterization of an Additional Splice Acceptor Site Introduced into CYP4B1 in Hominoidae during Evolution

CYP4B1 belongs to the cytochrome P450 family 4, one of the oldest P450 families whose members have been highly conserved throughout evolution. The CYP4 monooxygenases typically oxidize fatty acids to both inactive and active lipid mediators, although the endogenous ligand(s) is largely unknown. Duri...

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Detalles Bibliográficos
Autores principales: Schmidt, Eva M., Wiek, Constanze, Parkinson, Oliver T., Roellecke, Katharina, Freund, Marcel, Gombert, Michael, Lottmann, Nadine, Steward, Charles A., Kramm, Christof M., Yarov-Yarovoy, Vladimir, Rettie, Allan E., Hanenberg, Helmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565547/
https://www.ncbi.nlm.nih.gov/pubmed/26355749
http://dx.doi.org/10.1371/journal.pone.0137110

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