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Impact of Subunit Composition on the Uptake of α-Crystallin by Lens and Retina
Misfolded protein aggregation, including cataract, cause a significant amount of blindness worldwide. α-Crystallin is reported to bind misfolded proteins and prevent their aggregation. We hypothesize that supplementing retina and lens with α-crystallin may help to delay disease onset. The purpose of...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565700/ https://www.ncbi.nlm.nih.gov/pubmed/26355842 http://dx.doi.org/10.1371/journal.pone.0137659 |