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Neural transcriptome of constitutional Pten dysfunction in mice and its relevance to human idiopathic Autism Spectrum Disorder

Autism Spectrum Disorder (ASD) is a neurodevelopmental condition with a clear, but heterogeneous, genetic component. Germline mutations in the tumor suppressor PTEN are a well-established risk factor for ASD with macrocephaly, and conditional Pten mouse models have impaired social behavior and brain...

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Detalles Bibliográficos
Autores principales:	Tilot, Amanda K, Bebek, Gurkan, Niazi, Farshad, Altemus, Jessica, Romigh, Todd, Frazier, Thomas W, Eng, Charis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565786/ https://www.ncbi.nlm.nih.gov/pubmed/25754085 http://dx.doi.org/10.1038/mp.2015.17

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