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Akt and Hippo Pathways in Ewing's Sarcoma Tumors and Their Prognostic Significance

Background: Ewing's sarcoma tumor is an aggressive malignancy of bone and soft tissue in children and young adults. Despite advances in modern therapy, metastasis occurs and results in high mortality. Intracellular molecules Yap, Akt, mTOR, and Erk are signaling pathway members that regulate th...

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Detalles Bibliográficos
Autores principales: Ahmed, Atif A., Abedalthagafi, Malak, Anwar, Ahmed E., Bui, Marilyn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565850/
https://www.ncbi.nlm.nih.gov/pubmed/26366214
http://dx.doi.org/10.7150/jca.12703