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Akt and Hippo Pathways in Ewing's Sarcoma Tumors and Their Prognostic Significance
Background: Ewing's sarcoma tumor is an aggressive malignancy of bone and soft tissue in children and young adults. Despite advances in modern therapy, metastasis occurs and results in high mortality. Intracellular molecules Yap, Akt, mTOR, and Erk are signaling pathway members that regulate th...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565850/ https://www.ncbi.nlm.nih.gov/pubmed/26366214 http://dx.doi.org/10.7150/jca.12703 |