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The Regulation of Matrix Metalloproteinase Expression and the Role of Discoidin Domain Receptor 1/2 Signalling in Zoledronate-treated PC3 Cells

Discoidin Domain Receptors (DDR1/DDR2) are tyrosine kinase receptors which are activated by collagen. DDR signalling regulates cell migration, proliferation, apoptosis and matrix metalloproteinase (MMP) production. MMPs degrade extracellular matrix (ECM) and play essential role in tumor growth, inva...

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Detalles Bibliográficos
Autores principales:	Reel, Buket, Korkmaz, Ceren Gonen, Arun, Mehmet Zuhuri, Yildirim, Gokce, Ogut, Deniz, Kaymak, Aysegul, Micili, Serap Cilaker, Ergur, Bekir Ugur
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565852/ https://www.ncbi.nlm.nih.gov/pubmed/26366216 http://dx.doi.org/10.7150/jca.12733

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