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Weaknesses and Pitfalls of Using Mice and Rats in Cancer Chemoprevention Studies

Many studies, using different chemical agents, have shown excellent cancer prevention efficacy in mice and rats. However, equivalent tests of cancer prevention in humans require decades of intake of the agents while the rodents' short lifespans cannot give us information of the long-term safety...

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Detalles Bibliográficos
Autores principales: Ma, Yukui, Jia, Yuping, Chen, Lichan, Ezeogu, Lewis, Yu, Baofa, Xu, Ningzhi, Liao, D. Joshua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565856/
https://www.ncbi.nlm.nih.gov/pubmed/26366220
http://dx.doi.org/10.7150/jca.12519