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LncReg: a reference resource for lncRNA-associated regulatory networks
Long non-coding RNAs (lncRNAs) are critical in the regulation of various biological processes. In recent years, plethora of lncRNAs have been identified in mammalian genomes through different approaches, and the researchers are constantly reporting the regulatory roles of these lncRNAs, which leads...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565966/ https://www.ncbi.nlm.nih.gov/pubmed/26363021 http://dx.doi.org/10.1093/database/bav083 |
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author | Zhou, Zhong Shen, Yi Khan, Muhammad Riaz Li, Ao |
author_facet | Zhou, Zhong Shen, Yi Khan, Muhammad Riaz Li, Ao |
author_sort | Zhou, Zhong |
collection | PubMed |
description | Long non-coding RNAs (lncRNAs) are critical in the regulation of various biological processes. In recent years, plethora of lncRNAs have been identified in mammalian genomes through different approaches, and the researchers are constantly reporting the regulatory roles of these lncRNAs, which leads to complexity of literature about particular lncRNAs. Therefore, for the convenience of the researchers, we collected regulatory relationships of the lncRNAs and built a database called ‘LncReg’. This database is developed by collecting 1081 validated lncRNA-associated regulatory entries, including 258 non-redundant lncRNAs and 571 non-redundant genes. With regulatory relationships information, LncReg can provide overall perspectives of regulatory networks of lncRNAs and comprehensive data for bioinformatics research, which is useful for understanding the functional roles of lncRNAs. Database URL: http://bioinformatics.ustc.edu.cn/lncreg/ |
format | Online Article Text |
id | pubmed-4565966 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-45659662015-09-15 LncReg: a reference resource for lncRNA-associated regulatory networks Zhou, Zhong Shen, Yi Khan, Muhammad Riaz Li, Ao Database (Oxford) Original Article Long non-coding RNAs (lncRNAs) are critical in the regulation of various biological processes. In recent years, plethora of lncRNAs have been identified in mammalian genomes through different approaches, and the researchers are constantly reporting the regulatory roles of these lncRNAs, which leads to complexity of literature about particular lncRNAs. Therefore, for the convenience of the researchers, we collected regulatory relationships of the lncRNAs and built a database called ‘LncReg’. This database is developed by collecting 1081 validated lncRNA-associated regulatory entries, including 258 non-redundant lncRNAs and 571 non-redundant genes. With regulatory relationships information, LncReg can provide overall perspectives of regulatory networks of lncRNAs and comprehensive data for bioinformatics research, which is useful for understanding the functional roles of lncRNAs. Database URL: http://bioinformatics.ustc.edu.cn/lncreg/ Oxford University Press 2015-09-10 /pmc/articles/PMC4565966/ /pubmed/26363021 http://dx.doi.org/10.1093/database/bav083 Text en © The Author(s) 2015. Published by Oxford University Press. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Zhou, Zhong Shen, Yi Khan, Muhammad Riaz Li, Ao LncReg: a reference resource for lncRNA-associated regulatory networks |
title | LncReg: a reference resource for lncRNA-associated regulatory networks |
title_full | LncReg: a reference resource for lncRNA-associated regulatory networks |
title_fullStr | LncReg: a reference resource for lncRNA-associated regulatory networks |
title_full_unstemmed | LncReg: a reference resource for lncRNA-associated regulatory networks |
title_short | LncReg: a reference resource for lncRNA-associated regulatory networks |
title_sort | lncreg: a reference resource for lncrna-associated regulatory networks |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565966/ https://www.ncbi.nlm.nih.gov/pubmed/26363021 http://dx.doi.org/10.1093/database/bav083 |
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