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Distinct transcriptional responses elicited by unfolded nuclear or cytoplasmic protein in mammalian cells

Eukaryotic cells possess a variety of signaling pathways that prevent accumulation of unfolded and misfolded proteins. Chief among these is the heat shock response (HSR), which is assumed to respond to unfolded proteins in the cytosol and nucleus alike. In this study, we probe this axiom further usi...

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Detalles Bibliográficos
Autores principales:	Miyazaki, Yusuke, Chen, Ling-chun, Chu, Bernard W, Swigut, Tomek, Wandless, Thomas J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2015
Materias:	Biochemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566031/ https://www.ncbi.nlm.nih.gov/pubmed/26314864 http://dx.doi.org/10.7554/eLife.07687

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