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A Role for Fragment-Based Drug Design in Developing Novel Lead Compounds for Central Nervous System Targets
Hundreds of millions of U.S. dollars are invested in the research and development of a single drug. Lead compound development is an area ripe for new design strategies. Therapeutic lead candidates have been traditionally found using high-throughput in vitro pharmacological screening, a costly method...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566055/ https://www.ncbi.nlm.nih.gov/pubmed/26441817 http://dx.doi.org/10.3389/fneur.2015.00197 |