Downregulation of PHEX in multibacillary leprosy patients: observational cross-sectional study

BACKGROUND: Peripheral nerve injury and bone lesions, well known leprosy complications, lead to deformities and incapacities. The phosphate-regulating gene with homologies to endopeptidase on the X chromosome (PHEX) encodes a homonymous protein (PHEX) implicated in bone metabolism. PHEX/PHEX alterat...

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Detalles Bibliográficos
Autores principales: Silva, Sandra R. Boiça, Illarramendi, Ximena, Tempone, Antonio J., Silva, Pedro H. L., Nery, José A. C., Monteiro, Alexandra M. V., Pessolani, Maria Cristina V., Boasquevisque, Edson, Sarno, Euzenir N., Pereira, Geraldo M. B., Esquenazi, Danuza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566286/
https://www.ncbi.nlm.nih.gov/pubmed/26362198
http://dx.doi.org/10.1186/s12967-015-0651-5

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