Effects of cytochalasin congeners, microtubule-directed agents, and doxorubicin alone or in combination against human ovarian carcinoma cell lines in vitro

BACKGROUND: Although the actin cytoskeleton is vital for carcinogenesis and subsequent pathology, no microfilament-directed agent has been approved for cancer chemotherapy. One of the most studied classes of microfilament-directed agents has been the cytochalasins, mycotoxins known to disrupt the fo...

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Detalles Bibliográficos
Autores principales: Trendowski, Matthew, Christen, Timothy D., Acquafondata, Christopher, Fondy, Thomas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566295/
https://www.ncbi.nlm.nih.gov/pubmed/26357852
http://dx.doi.org/10.1186/s12885-015-1619-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566295/
https://www.ncbi.nlm.nih.gov/pubmed/26357852
http://dx.doi.org/10.1186/s12885-015-1619-9

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