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Effects of cytochalasin congeners, microtubule-directed agents, and doxorubicin alone or in combination against human ovarian carcinoma cell lines in vitro
BACKGROUND: Although the actin cytoskeleton is vital for carcinogenesis and subsequent pathology, no microfilament-directed agent has been approved for cancer chemotherapy. One of the most studied classes of microfilament-directed agents has been the cytochalasins, mycotoxins known to disrupt the fo...
Autores principales: | Trendowski, Matthew, Christen, Timothy D., Acquafondata, Christopher, Fondy, Thomas P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566295/ https://www.ncbi.nlm.nih.gov/pubmed/26357852 http://dx.doi.org/10.1186/s12885-015-1619-9 |
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