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Clinical profile of diabetic ketoacidosis in tertiary care hospital of Eastern Nepal
INTRODUCTION: Diabetes ketoacidoisis (DKA) is characterized by hyperketonaemia, metabolic acidosis, and hyperglycemia. Aims: The aim of this study was to describe the demographic profile, clinical characterstics of patients admitted with diabetic ketoacidosis in BPKIHS, medical ward. SETTINGS AND DE...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566352/ https://www.ncbi.nlm.nih.gov/pubmed/26425481 http://dx.doi.org/10.4103/2230-8210.163208 |
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author | Maskey, Robin Shakya, Dhana Ratna Nikesh, Bista Krishna, Kumar Agrawal Lavaju, Poonam Kattel, Vivek Arjyal, Lubina Karki, Prahlad |
author_facet | Maskey, Robin Shakya, Dhana Ratna Nikesh, Bista Krishna, Kumar Agrawal Lavaju, Poonam Kattel, Vivek Arjyal, Lubina Karki, Prahlad |
author_sort | Maskey, Robin |
collection | PubMed |
description | INTRODUCTION: Diabetes ketoacidoisis (DKA) is characterized by hyperketonaemia, metabolic acidosis, and hyperglycemia. Aims: The aim of this study was to describe the demographic profile, clinical characterstics of patients admitted with diabetic ketoacidosis in BPKIHS, medical ward. SETTINGS AND DESIGN: The hospital based descriptive study. MATERIALS AND METHODS: We took all the patients admitted with a diagnosis of diabetic ketoacidosis (DKA) as defined ADA 2006 consensus statement in medical ward from January 2010 to December 2010. The statistical operations was done through Manufactured by IBM Corp. RESULTS: Only sixteen patients (7 type 1 and 9 type 2DM) were with DKA. When compared to the 16 subjects with type 1 DM, the type 2 were older (56.8 s 25.7 years) and had a significantly higher PH levels (7.11 s 7.28 P = 0.04). The mean body mass index was 20.5±2.44 in both Type 1 and type 2 DM. Four were on diet control and Insulin respectively. Five were on oral hypoglycemic agents (OHA) and three on both (insulin and OHA). Infection was most common precipitating factor (56.25%) followed by poor drug compliance (37.5%) and first presentation (6.25%). CONCLUSIONS: We found majority of patients were type 2 DM. Metabolic acidosis has significant association in both type of diabetic. We found infection was the most common precipitating factor for DKA. |
format | Online Article Text |
id | pubmed-4566352 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-45663522015-09-30 Clinical profile of diabetic ketoacidosis in tertiary care hospital of Eastern Nepal Maskey, Robin Shakya, Dhana Ratna Nikesh, Bista Krishna, Kumar Agrawal Lavaju, Poonam Kattel, Vivek Arjyal, Lubina Karki, Prahlad Indian J Endocrinol Metab Original Article INTRODUCTION: Diabetes ketoacidoisis (DKA) is characterized by hyperketonaemia, metabolic acidosis, and hyperglycemia. Aims: The aim of this study was to describe the demographic profile, clinical characterstics of patients admitted with diabetic ketoacidosis in BPKIHS, medical ward. SETTINGS AND DESIGN: The hospital based descriptive study. MATERIALS AND METHODS: We took all the patients admitted with a diagnosis of diabetic ketoacidosis (DKA) as defined ADA 2006 consensus statement in medical ward from January 2010 to December 2010. The statistical operations was done through Manufactured by IBM Corp. RESULTS: Only sixteen patients (7 type 1 and 9 type 2DM) were with DKA. When compared to the 16 subjects with type 1 DM, the type 2 were older (56.8 s 25.7 years) and had a significantly higher PH levels (7.11 s 7.28 P = 0.04). The mean body mass index was 20.5±2.44 in both Type 1 and type 2 DM. Four were on diet control and Insulin respectively. Five were on oral hypoglycemic agents (OHA) and three on both (insulin and OHA). Infection was most common precipitating factor (56.25%) followed by poor drug compliance (37.5%) and first presentation (6.25%). CONCLUSIONS: We found majority of patients were type 2 DM. Metabolic acidosis has significant association in both type of diabetic. We found infection was the most common precipitating factor for DKA. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4566352/ /pubmed/26425481 http://dx.doi.org/10.4103/2230-8210.163208 Text en Copyright: © Indian Journal of Endocrinology and Metabolism http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Maskey, Robin Shakya, Dhana Ratna Nikesh, Bista Krishna, Kumar Agrawal Lavaju, Poonam Kattel, Vivek Arjyal, Lubina Karki, Prahlad Clinical profile of diabetic ketoacidosis in tertiary care hospital of Eastern Nepal |
title | Clinical profile of diabetic ketoacidosis in tertiary care hospital of Eastern Nepal |
title_full | Clinical profile of diabetic ketoacidosis in tertiary care hospital of Eastern Nepal |
title_fullStr | Clinical profile of diabetic ketoacidosis in tertiary care hospital of Eastern Nepal |
title_full_unstemmed | Clinical profile of diabetic ketoacidosis in tertiary care hospital of Eastern Nepal |
title_short | Clinical profile of diabetic ketoacidosis in tertiary care hospital of Eastern Nepal |
title_sort | clinical profile of diabetic ketoacidosis in tertiary care hospital of eastern nepal |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566352/ https://www.ncbi.nlm.nih.gov/pubmed/26425481 http://dx.doi.org/10.4103/2230-8210.163208 |
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