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Point and Interval Estimators of the Target Dose in Clinical Dose-Finding Studies with Active Control
In a clinical dose finding study with active control a new drug with several dose levels is compared with an active comparator drug. The main focus of such studies often lies on the estimation of a target dose that leads to the same efficacy as the control. This article investigates the finite sampl...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566885/ https://www.ncbi.nlm.nih.gov/pubmed/24918730 http://dx.doi.org/10.1080/10543406.2014.920343 |