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Polymorphisms in MTHFD1 Gene and Susceptibility to Neural Tube Defects: A Case-Control Study in a Chinese Han Population with Relatively Low Folate Levels

BACKGROUND: The polymorphism of methylenetetrahydrofolate dehydrogenase (MTHFD1) has been reported as a risk factor for neural tube defects (NTDs). In the present study, we aimed to investigate whether the single-nucleotide polymorphisms (SNPs) of MTHFD1 gene are associated with NTDs in a Chinese po...

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Detalles Bibliográficos
Autores principales: Wu, Jian, Bao, Yihua, Lu, Xiaolin, Wu, Lihua, Zhang, Ting, Guo, Jin, Yang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566945/
https://www.ncbi.nlm.nih.gov/pubmed/26343515
http://dx.doi.org/10.12659/MSM.895155