Promising effects of 3rd line cyclophosphamide, adriamycin and vincristine (CAV) and 4th line ifosfamide and carboplatin chemotherapy in refractory small cell lung cancer

Third and fourth line chemotherapy agents are not helpful in the setting of extensive stage small cell lung cancer (SCLC). We describe the case of a 43-year-old Korean patient with T4N3M1b extensive stage SCLC who responded remarkably well to treatment and experienced a prolonged progression-free su...

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Autores principales: Jung, Sang Ok, Kim, Sun Young, Kim, Ju-Ock, Jung, Sung Soo, Park, Hee Sun, Moon, Jae Young, Kim, Sung Min, Lee, Jeong Eun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567014/
https://www.ncbi.nlm.nih.gov/pubmed/26445616
http://dx.doi.org/10.1111/1759-7714.12198
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author Jung, Sang Ok
Kim, Sun Young
Kim, Ju-Ock
Jung, Sung Soo
Park, Hee Sun
Moon, Jae Young
Kim, Sung Min
Lee, Jeong Eun
author_facet Jung, Sang Ok
Kim, Sun Young
Kim, Ju-Ock
Jung, Sung Soo
Park, Hee Sun
Moon, Jae Young
Kim, Sung Min
Lee, Jeong Eun
author_sort Jung, Sang Ok
collection PubMed
description Third and fourth line chemotherapy agents are not helpful in the setting of extensive stage small cell lung cancer (SCLC). We describe the case of a 43-year-old Korean patient with T4N3M1b extensive stage SCLC who responded remarkably well to treatment and experienced a prolonged progression-free survival (PFS) period following treatment with fourth line ifosfamide and carboplatin after experiencing disease progression with three previous regimens. Additionally, third line cyclophosphamide, doxorubicin (Adriamycin), and vincristine demonstrated long-term PFS periods.
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spelling pubmed-45670142015-10-06 Promising effects of 3rd line cyclophosphamide, adriamycin and vincristine (CAV) and 4th line ifosfamide and carboplatin chemotherapy in refractory small cell lung cancer Jung, Sang Ok Kim, Sun Young Kim, Ju-Ock Jung, Sung Soo Park, Hee Sun Moon, Jae Young Kim, Sung Min Lee, Jeong Eun Thorac Cancer Case Reports Third and fourth line chemotherapy agents are not helpful in the setting of extensive stage small cell lung cancer (SCLC). We describe the case of a 43-year-old Korean patient with T4N3M1b extensive stage SCLC who responded remarkably well to treatment and experienced a prolonged progression-free survival (PFS) period following treatment with fourth line ifosfamide and carboplatin after experiencing disease progression with three previous regimens. Additionally, third line cyclophosphamide, doxorubicin (Adriamycin), and vincristine demonstrated long-term PFS periods. John Wiley & Sons, Ltd 2015-09 2015-01-27 /pmc/articles/PMC4567014/ /pubmed/26445616 http://dx.doi.org/10.1111/1759-7714.12198 Text en © 2015 The Authors. Thoracic Cancer published by Tianjin Lung Cancer Institute and Wiley Publishing Asia Pty Ltd. http://creativecommons.org/licenses/by-nc/4.0/ This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Reports
Jung, Sang Ok
Kim, Sun Young
Kim, Ju-Ock
Jung, Sung Soo
Park, Hee Sun
Moon, Jae Young
Kim, Sung Min
Lee, Jeong Eun
Promising effects of 3rd line cyclophosphamide, adriamycin and vincristine (CAV) and 4th line ifosfamide and carboplatin chemotherapy in refractory small cell lung cancer
title Promising effects of 3rd line cyclophosphamide, adriamycin and vincristine (CAV) and 4th line ifosfamide and carboplatin chemotherapy in refractory small cell lung cancer
title_full Promising effects of 3rd line cyclophosphamide, adriamycin and vincristine (CAV) and 4th line ifosfamide and carboplatin chemotherapy in refractory small cell lung cancer
title_fullStr Promising effects of 3rd line cyclophosphamide, adriamycin and vincristine (CAV) and 4th line ifosfamide and carboplatin chemotherapy in refractory small cell lung cancer
title_full_unstemmed Promising effects of 3rd line cyclophosphamide, adriamycin and vincristine (CAV) and 4th line ifosfamide and carboplatin chemotherapy in refractory small cell lung cancer
title_short Promising effects of 3rd line cyclophosphamide, adriamycin and vincristine (CAV) and 4th line ifosfamide and carboplatin chemotherapy in refractory small cell lung cancer
title_sort promising effects of 3rd line cyclophosphamide, adriamycin and vincristine (cav) and 4th line ifosfamide and carboplatin chemotherapy in refractory small cell lung cancer
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567014/
https://www.ncbi.nlm.nih.gov/pubmed/26445616
http://dx.doi.org/10.1111/1759-7714.12198
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