Downregulation of RND3/RhoE in glioblastoma patients promotes tumorigenesis through augmentation of notch transcriptional complex activity

Activation of Notch signaling contributes to glioblastoma multiform (GBM) tumorigenesis. However, the molecular mechanism that promotes the Notch signaling augmentation during GBM genesis remains largely unknown. Identification of new factors that regulate Notch signaling is critical for tumor treat...

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Detalles Bibliográficos
Autores principales: Liu, Baohui, Lin, Xi, Yang, Xiangsheng, Dong, Huimin, Yue, Xiaojing, Andrade, Kelsey C, Guo, Zhentao, Yang, Jian, Wu, Liquan, Zhu, Xiaonan, Zhang, Shenqi, Tian, Daofeng, Wang, Junmin, Cai, Qiang, Chen, Qizuan, Mao, Shanping, Chen, Qianxue, Chang, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567025/
https://www.ncbi.nlm.nih.gov/pubmed/26108681
http://dx.doi.org/10.1002/cam4.484

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