The Cyclophilin A-CD147 complex promotes bone marrow colonization of B-cell malignancies: implications for therapy

B-cell malignancies frequently colonizes the bone marrow (BM). The mechanisms responsible for this preferential homing are not entirely known. Using multiple myeloma (MM) as a model of a terminally differentiated B-cell malignancy that selectively colonizes the BM, we demonstrated that BM endothelia...

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Detalles Bibliográficos
Autores principales: Zhu, Di, Wang, Zhongqiu, Zhao, Jian-Jun, Calimeri, Teresa, Meng, Jiang, Hideshima, Teru, Fulciniti, Mariateresa, Kang, Yue, Ficarro, Scott, Tai, Yu-Tzu, Hunter, Zachary, McMilin, Douglas, Tong, Haoxuan, Mitsiades, Constantine S., Wu, Catherine, Treon, Steven, Dorfman, David M., Pinkus, Geraldine, Munshi, Nikhil, Tassone, Pierfrancesco, Marto, Jarrod, Anderson, Kenneth, Carrasco, Ruben D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567046/
https://www.ncbi.nlm.nih.gov/pubmed/26005854
http://dx.doi.org/10.1038/nm.3867

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