Adult T-Cell Leukemia/Lymphoma in a Caucasian Patient After Sexual Transmission of Human T-Cell Lymphotropic Virus Type 1

Adult T-cell leukemia/lymphoma (ATLL), a T-cell neoplasm caused by human T-cell lymphotropic virus type 1 (HTLV-1), develops in the majority of cases in individuals who were infected with HTLV-1 as young children, by their mother during prolonged breastfeeding. We report the case of a Caucasian Fren...

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Autores principales: Sibon, David, Cassar, Olivier, Duga, Isabelle, Brouzes, Chantal, Ghez, David, Pasquier, Christophe, Sibon, Claire, Desrames, Alexandra, Mortreux, Franck, Wattel, Eric, Bazarbachi, Ali, Gessain, Antoine, Hermine, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567067/
https://www.ncbi.nlm.nih.gov/pubmed/26380333
http://dx.doi.org/10.1093/ofid/ofv032
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author Sibon, David
Cassar, Olivier
Duga, Isabelle
Brouzes, Chantal
Ghez, David
Pasquier, Christophe
Sibon, Claire
Desrames, Alexandra
Mortreux, Franck
Wattel, Eric
Bazarbachi, Ali
Gessain, Antoine
Hermine, Olivier
author_facet Sibon, David
Cassar, Olivier
Duga, Isabelle
Brouzes, Chantal
Ghez, David
Pasquier, Christophe
Sibon, Claire
Desrames, Alexandra
Mortreux, Franck
Wattel, Eric
Bazarbachi, Ali
Gessain, Antoine
Hermine, Olivier
author_sort Sibon, David
collection PubMed
description Adult T-cell leukemia/lymphoma (ATLL), a T-cell neoplasm caused by human T-cell lymphotropic virus type 1 (HTLV-1), develops in the majority of cases in individuals who were infected with HTLV-1 as young children, by their mother during prolonged breastfeeding. We report the case of a Caucasian French man, whose parents were HTLV-1-seronegative and who developed ATLL after HTLV-1 sexual transmission by a Cameroonian woman. This hypothesis was corroborated by genotyping of the patient's virus, which revealed an HTLV-1B strain, found only in Central Africa, especially in Cameroon. Thus, ATLL may develop after HTLV-1 infection during adulthood, outside breastfeeding.
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spelling pubmed-45670672015-09-15 Adult T-Cell Leukemia/Lymphoma in a Caucasian Patient After Sexual Transmission of Human T-Cell Lymphotropic Virus Type 1 Sibon, David Cassar, Olivier Duga, Isabelle Brouzes, Chantal Ghez, David Pasquier, Christophe Sibon, Claire Desrames, Alexandra Mortreux, Franck Wattel, Eric Bazarbachi, Ali Gessain, Antoine Hermine, Olivier Open Forum Infect Dis Brief Reports Adult T-cell leukemia/lymphoma (ATLL), a T-cell neoplasm caused by human T-cell lymphotropic virus type 1 (HTLV-1), develops in the majority of cases in individuals who were infected with HTLV-1 as young children, by their mother during prolonged breastfeeding. We report the case of a Caucasian French man, whose parents were HTLV-1-seronegative and who developed ATLL after HTLV-1 sexual transmission by a Cameroonian woman. This hypothesis was corroborated by genotyping of the patient's virus, which revealed an HTLV-1B strain, found only in Central Africa, especially in Cameroon. Thus, ATLL may develop after HTLV-1 infection during adulthood, outside breastfeeding. Oxford University Press 2015-03-06 /pmc/articles/PMC4567067/ /pubmed/26380333 http://dx.doi.org/10.1093/ofid/ofv032 Text en © The Author 2015. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com.
spellingShingle Brief Reports
Sibon, David
Cassar, Olivier
Duga, Isabelle
Brouzes, Chantal
Ghez, David
Pasquier, Christophe
Sibon, Claire
Desrames, Alexandra
Mortreux, Franck
Wattel, Eric
Bazarbachi, Ali
Gessain, Antoine
Hermine, Olivier
Adult T-Cell Leukemia/Lymphoma in a Caucasian Patient After Sexual Transmission of Human T-Cell Lymphotropic Virus Type 1
title Adult T-Cell Leukemia/Lymphoma in a Caucasian Patient After Sexual Transmission of Human T-Cell Lymphotropic Virus Type 1
title_full Adult T-Cell Leukemia/Lymphoma in a Caucasian Patient After Sexual Transmission of Human T-Cell Lymphotropic Virus Type 1
title_fullStr Adult T-Cell Leukemia/Lymphoma in a Caucasian Patient After Sexual Transmission of Human T-Cell Lymphotropic Virus Type 1
title_full_unstemmed Adult T-Cell Leukemia/Lymphoma in a Caucasian Patient After Sexual Transmission of Human T-Cell Lymphotropic Virus Type 1
title_short Adult T-Cell Leukemia/Lymphoma in a Caucasian Patient After Sexual Transmission of Human T-Cell Lymphotropic Virus Type 1
title_sort adult t-cell leukemia/lymphoma in a caucasian patient after sexual transmission of human t-cell lymphotropic virus type 1
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567067/
https://www.ncbi.nlm.nih.gov/pubmed/26380333
http://dx.doi.org/10.1093/ofid/ofv032
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