Effect of Intercurrent Infections and Vaccinations on Immune and Inflammatory Biomarkers Among Human Immunodeficiency Virus-Infected Adults on Suppressive Antiretroviral Therapy

We used generalized estimating equations to quantify the impact of recent vaccination or intercurrent infections on immune and inflammatory biomarkers among 144 human immunodeficiency virus (HIV)-infected adults with HIV RNA < 50 copies/mL on antiretroviral therapy. These events were associated w...

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Autores principales: Tan, Darrell H. S., Szadkowski, Leah, Raboud, Janet, Yi, Tae Joon, Shannon, Brett, Kaul, Rupert, Liles, W. Conrad, Walmsley, Sharon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567101/
https://www.ncbi.nlm.nih.gov/pubmed/26380337
http://dx.doi.org/10.1093/ofid/ofv036
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author Tan, Darrell H. S.
Szadkowski, Leah
Raboud, Janet
Yi, Tae Joon
Shannon, Brett
Kaul, Rupert
Liles, W. Conrad
Walmsley, Sharon
author_facet Tan, Darrell H. S.
Szadkowski, Leah
Raboud, Janet
Yi, Tae Joon
Shannon, Brett
Kaul, Rupert
Liles, W. Conrad
Walmsley, Sharon
author_sort Tan, Darrell H. S.
collection PubMed
description We used generalized estimating equations to quantify the impact of recent vaccination or intercurrent infections on immune and inflammatory biomarkers among 144 human immunodeficiency virus (HIV)-infected adults with HIV RNA < 50 copies/mL on antiretroviral therapy. These events were associated with a 2.244 µg/mL increase in high sensitivity C-reactive protein and should be routinely assessed in future studies.
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spelling pubmed-45671012015-09-14 Effect of Intercurrent Infections and Vaccinations on Immune and Inflammatory Biomarkers Among Human Immunodeficiency Virus-Infected Adults on Suppressive Antiretroviral Therapy Tan, Darrell H. S. Szadkowski, Leah Raboud, Janet Yi, Tae Joon Shannon, Brett Kaul, Rupert Liles, W. Conrad Walmsley, Sharon Open Forum Infect Dis Brief Reports We used generalized estimating equations to quantify the impact of recent vaccination or intercurrent infections on immune and inflammatory biomarkers among 144 human immunodeficiency virus (HIV)-infected adults with HIV RNA < 50 copies/mL on antiretroviral therapy. These events were associated with a 2.244 µg/mL increase in high sensitivity C-reactive protein and should be routinely assessed in future studies. Oxford University Press 2015-03-09 /pmc/articles/PMC4567101/ /pubmed/26380337 http://dx.doi.org/10.1093/ofid/ofv036 Text en © The Author 2015. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com.
spellingShingle Brief Reports
Tan, Darrell H. S.
Szadkowski, Leah
Raboud, Janet
Yi, Tae Joon
Shannon, Brett
Kaul, Rupert
Liles, W. Conrad
Walmsley, Sharon
Effect of Intercurrent Infections and Vaccinations on Immune and Inflammatory Biomarkers Among Human Immunodeficiency Virus-Infected Adults on Suppressive Antiretroviral Therapy
title Effect of Intercurrent Infections and Vaccinations on Immune and Inflammatory Biomarkers Among Human Immunodeficiency Virus-Infected Adults on Suppressive Antiretroviral Therapy
title_full Effect of Intercurrent Infections and Vaccinations on Immune and Inflammatory Biomarkers Among Human Immunodeficiency Virus-Infected Adults on Suppressive Antiretroviral Therapy
title_fullStr Effect of Intercurrent Infections and Vaccinations on Immune and Inflammatory Biomarkers Among Human Immunodeficiency Virus-Infected Adults on Suppressive Antiretroviral Therapy
title_full_unstemmed Effect of Intercurrent Infections and Vaccinations on Immune and Inflammatory Biomarkers Among Human Immunodeficiency Virus-Infected Adults on Suppressive Antiretroviral Therapy
title_short Effect of Intercurrent Infections and Vaccinations on Immune and Inflammatory Biomarkers Among Human Immunodeficiency Virus-Infected Adults on Suppressive Antiretroviral Therapy
title_sort effect of intercurrent infections and vaccinations on immune and inflammatory biomarkers among human immunodeficiency virus-infected adults on suppressive antiretroviral therapy
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567101/
https://www.ncbi.nlm.nih.gov/pubmed/26380337
http://dx.doi.org/10.1093/ofid/ofv036
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