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TLR9 Mediates Remote Liver Injury following Severe Renal Ischemia Reperfusion

Ischemia reperfusion injury is a common cause of acute kidney injury and is characterized by tubular damage. Mitochondrial DNA is released upon severe tissue injury and can act as a damage-associated molecular pattern via the innate immune receptor TLR9. Here, we investigated the role of TLR9 in the...

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Detalles Bibliográficos
Autores principales:	Bakker, Pieter J., Scantlebery, Angelique M., Butter, Loes M., Claessen, Nike, Teske, Gwendoline J. D., van der Poll, Tom, Florquin, Sandrine, Leemans, Jaklien C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567139/ https://www.ncbi.nlm.nih.gov/pubmed/26361210 http://dx.doi.org/10.1371/journal.pone.0137511

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