WWTR1 (WW domain containing transcription regulator 1)

WWTR1 (also called TAZ in publications. Therefore, TAZ is used in the following description) is a WW domaing-containing transcriptional coactivator, which was first identified as a 14-3-3 binding protein. TAZ is the downstream component in the Hippo pathway, and also has been found to interact with...

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Detalles Bibliográficos
Autores principales: Zhao, Yulei, Yang, Xiaolong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567323/
https://www.ncbi.nlm.nih.gov/pubmed/26366208
http://dx.doi.org/10.4267/2042/54169
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author Zhao, Yulei
Yang, Xiaolong
author_facet Zhao, Yulei
Yang, Xiaolong
author_sort Zhao, Yulei
collection PubMed
description WWTR1 (also called TAZ in publications. Therefore, TAZ is used in the following description) is a WW domaing-containing transcriptional coactivator, which was first identified as a 14-3-3 binding protein. TAZ is the downstream component in the Hippo pathway, and also has been found to interact with different pathways, such as Wnt, TGFbeta, etc. TAZ is involved in mesenchymal stem cell differentiation as well as tumorigenesis. High level of TAZ has been found in different cancers, such as breast cancer, colon cancer, lung cancer, etc.
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spelling pubmed-45673232015-09-11 WWTR1 (WW domain containing transcription regulator 1) Zhao, Yulei Yang, Xiaolong Atlas Genet Cytogenet Oncol Haematol Article WWTR1 (also called TAZ in publications. Therefore, TAZ is used in the following description) is a WW domaing-containing transcriptional coactivator, which was first identified as a 14-3-3 binding protein. TAZ is the downstream component in the Hippo pathway, and also has been found to interact with different pathways, such as Wnt, TGFbeta, etc. TAZ is involved in mesenchymal stem cell differentiation as well as tumorigenesis. High level of TAZ has been found in different cancers, such as breast cancer, colon cancer, lung cancer, etc. 2014-11-01 /pmc/articles/PMC4567323/ /pubmed/26366208 http://dx.doi.org/10.4267/2042/54169 Text en http://creativecommons.org/licenses/by/2.0/ This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 2.0 France Licence.
spellingShingle Article
Zhao, Yulei
Yang, Xiaolong
WWTR1 (WW domain containing transcription regulator 1)
title WWTR1 (WW domain containing transcription regulator 1)
title_full WWTR1 (WW domain containing transcription regulator 1)
title_fullStr WWTR1 (WW domain containing transcription regulator 1)
title_full_unstemmed WWTR1 (WW domain containing transcription regulator 1)
title_short WWTR1 (WW domain containing transcription regulator 1)
title_sort wwtr1 (ww domain containing transcription regulator 1)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567323/
https://www.ncbi.nlm.nih.gov/pubmed/26366208
http://dx.doi.org/10.4267/2042/54169
work_keys_str_mv AT zhaoyulei wwtr1wwdomaincontainingtranscriptionregulator1
AT yangxiaolong wwtr1wwdomaincontainingtranscriptionregulator1

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