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G2/M Cell Cycle Arrest and Tumor Selective Apoptosis of Acute Leukemia Cells by a Promising Benzophenone Thiosemicarbazone Compound
Anti-mitotic therapies have been considered a hallmark in strategies against abnormally proliferating cells. Focusing on the extensively studied family of thiosemicarbazone (TSC) compounds, we have previously identified 4,4’-dimethoxybenzophenone thiosemicarbazone (T44Bf) as a promising pharmacologi...
Autores principales: | Cabrera, Maia, Gomez, Natalia, Remes Lenicov, Federico, Echeverría, Emiliana, Shayo, Carina, Moglioni, Albertina, Fernández, Natalia, Davio, Carlos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567328/ https://www.ncbi.nlm.nih.gov/pubmed/26360247 http://dx.doi.org/10.1371/journal.pone.0136878 |
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