Cargando…

Epigenetic synergy between decitabine and platinum derivatives

BACKGROUND: Aberrant epigenetic silencing of tumor suppressor genes has been recognized as a driving force in cancer. Epigenetic drugs such as the DNA methylation inhibitor decitabine reactivate genes and are effective in myeloid leukemia, but resistance often develops and efficacy in solid tumors i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qin, Taichun, Si, Jiali, Raynal, Noël J-M, Wang, Xiaodan, Gharibyan, Vazganush, Ahmed, Saira, Hu, Xin, Jin, Chunlei, Lu, Yue, Shu, Jingmin, Estecio, Marcos RH, Jelinek, Jaroslav, Issa, Jean-Pierre J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567801/ https://www.ncbi.nlm.nih.gov/pubmed/26366234 http://dx.doi.org/10.1186/s13148-015-0131-z

Ejemplares similares

Mechanisms of Resistance to Decitabine in the Myelodysplastic Syndrome
por: Qin, Taichun, et al.
Publicado: (2011)

LINE-1 Hypomethylation in Cancer Is Highly Variable and Inversely Correlated with Microsatellite Instability
por: Estécio, Marcos R.H., et al.
Publicado: (2007)

Aberrant DNA Methylation Is Associated with Disease Progression, Resistance to Imatinib and Shortened Survival in Chronic Myelogenous Leukemia
por: Jelinek, Jaroslav, et al.
Publicado: (2011)

Repetitive elements and enforced transcriptional repression co-operate to enhance DNA methylation spreading into a promoter CpG-island
por: Zhang, Yan, et al.
Publicado: (2012)

TET1 is a maintenance DNA demethylase that prevents methylation spreading in differentiated cells
por: Jin, Chunlei, et al.
Publicado: (2014)

Architecture of epigenetic reprogramming following Twist1-mediated epithelial-mesenchymal transition
por: Malouf, Gabriel G, et al.
Publicado: (2013)

Age-related epigenetic drift in the pathogenesis of MDS and AML
por: Maegawa, Shinji, et al.
Publicado: (2014)

Epigenetic mechanisms of induced pluripotency
por: Gładych, Marta, et al.
Publicado: (2015)

Tackling the methylome: recent methodological advances in genome-wide methylation profiling
por: Estécio, Marcos RH, et al.
Publicado: (2009)

Decitabine reactivated pathways in platinum resistant ovarian cancer
por: Fang, Fang, et al.
Publicado: (2014)

Impact of decitabine on immunohistochemistry expression of the putative tumor suppressor genes FHIT, WWOX, FUS1 and PTEN in clinical tumor samples
por: Stewart, David J, et al.
Publicado: (2014)

Decitabine: a historical review of the development of an epigenetic drug
por: de Vos, Dick, et al.
Publicado: (2005)

Decitabine impact on the endocytosis regulator RhoA, the folate carriers RFC1 and FOLR1, and the glucose transporter GLUT4 in human tumors
por: Stewart, David J, et al.
Publicado: (2014)

Antimicrobial Synergy of Silver-Platinum Nanohybrids With Antibiotics
por: Ranpariya, Bansi, et al.
Publicado: (2021)

Epigenetic Anti‐Cancer Treatment With a Stabilized Carbocyclic Decitabine Analogue
por: Traube, Franziska R., et al.
Publicado: (2022)

Integrative Analysis of Epigenetic Modulation in Melanoma Cell Response to Decitabine: Clinical Implications
por: Halaban, Ruth, et al.
Publicado: (2009)

Epigenetic preconditioning with decitabine sensitizes glioblastoma to temozolomide via induction of MLH1
por: Gallitto, Matthew, et al.
Publicado: (2020)

Frequent Alteration of MLL3 Frameshift Mutations in Microsatellite Deficient Colorectal Cancer
por: Watanabe, Yoshiyuki, et al.
Publicado: (2011)

A multicenter, randomized study of decitabine as epigenetic priming with induction chemotherapy in children with AML
por: Gore, Lia, et al.
Publicado: (2017)

Di-O-lauroyl-decitabine-lipid nanocapsules: toward extending decitabine activity
por: Briot, Thomas, et al.
Publicado: (2019)

Combined inhibition of histone deacetylase and cytidine deaminase improves epigenetic potency of decitabine in colorectal adenocarcinomas
por: Tang, Zijiao, et al.
Publicado: (2023)

DNA Methylation Profiles of Primary Colorectal Carcinoma and Matched Liver Metastasis
por: Konishi, Kazuo, et al.
Publicado: (2011)

Carboplatin with Decitabine Therapy, in Recurrent Platinum Resistant Ovarian Cancer, Alters Circulating miRNAs Concentrations: A Pilot Study
por: Benson, Eric A., et al.
Publicado: (2015)

Decitabine in the treatment of myelodysplastic syndromes
por: Saba, Hussain I
Publicado: (2007)

Decitabine/Cedazuridine: First Approval
por: Dhillon, Sohita
Publicado: (2021)

Treatment of resistant metastatic melanoma using sequential epigenetic therapy (decitabine and panobinostat) combined with chemotherapy (temozolomide)
por: Xia, Chang, et al.
Publicado: (2014)

Epigenetic Therapy of Non-Small Cell Lung Cancer Using Decitabine (5-Aza-2′-Deoxycytidine)
por: Momparler, Richard L.
Publicado: (2013)

Decitabine enhances the tumoricidal potential of TRAIL via the epigenetic regulation of death receptor 4 in gastric cancer
por: Li, Lin, et al.
Publicado: (2022)

Development of a novel cell-based assay system EPISSAY for screening epigenetic drugs and liposome formulated decitabine
por: Lim, Sue Ping, et al.
Publicado: (2013)

Targeting epigenetics for treatment of BRAF mutated metastatic melanoma with decitabine in combination with vemurafenib: A phase lb study
por: Zakharia, Yousef, et al.
Publicado: (2017)

Low-dose decitabine priming endows CAR T cells with enhanced and persistent antitumour potential via epigenetic reprogramming
por: Wang, Yao, et al.
Publicado: (2021)

An Sp1/Sp3 Binding Polymorphism Confers Methylation Protection
por: Boumber, Yanis A., et al.
Publicado: (2008)

Correction to: Decitabine/Cedazuridine: First Approval
por: Dhillon, Sohita
Publicado: (2020)

Venetoclax with decitabine versus decitabine monotherapy in elderly acute myeloid leukemia: a propensity score-matched analysis
por: Kwag, Daehun, et al.
Publicado: (2022)

Highly active and durable methanol oxidation electrocatalyst based on the synergy of platinum–nickel hydroxide–graphene
por: Huang, Wenjing, et al.
Publicado: (2015)

Synergistic Cytotoxic Effect of L-Asparaginase Combined with Decitabine as a Demethylating Agent in Pediatric T-ALL, with Specific Epigenetic Signature
por: Serravalle, Salvatore, et al.
Publicado: (2016)

Decitabine-Mediated Epigenetic Reprograming Enhances Anti-leukemia Efficacy of CD123-Targeted Chimeric Antigen Receptor T-Cells
por: You, Liangshun, et al.
Publicado: (2020)

Adjuvant Epigenetic Therapy of Decitabine and Suberoylanilide Hydroxamic Acid Exerts Anti-Neoplastic Effects in Acute Myeloid Leukemia Cells
por: Abou Najem, Sonia, et al.
Publicado: (2019)

Epigenetic and antitumor effects of platinum(IV)-octanoato conjugates
por: Novohradsky, Vojtech, et al.
Publicado: (2017)

PD-L1 and MRN synergy in platinum-based chemoresistance of head and neck squamous cell carcinoma
por: Shen, Bin, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_lai2to5mos4g5q6llr78878v44