Translational repression protects human keratinocytes from UVB-induced apoptosis through a discordant eIF2 kinase stress response

This study delineates the mechanisms by which ultraviolet B (UVB) regulates protein synthesis in human keratinocytes and the importance of translational control in cell survival. Translation initiation is regulated by phosphorylation of eukaryotic initiation factor 2 (eIF2~P), which causes decreased...

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Detalles Bibliográficos
Autores principales: Collier, Ann E., Wek, Ronald C., Spandau, Dan F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567905/
https://www.ncbi.nlm.nih.gov/pubmed/25950825
http://dx.doi.org/10.1038/jid.2015.177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567905/
https://www.ncbi.nlm.nih.gov/pubmed/25950825
http://dx.doi.org/10.1038/jid.2015.177

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