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Translational repression protects human keratinocytes from UVB-induced apoptosis through a discordant eIF2 kinase stress response
This study delineates the mechanisms by which ultraviolet B (UVB) regulates protein synthesis in human keratinocytes and the importance of translational control in cell survival. Translation initiation is regulated by phosphorylation of eukaryotic initiation factor 2 (eIF2~P), which causes decreased...
Autores principales: | Collier, Ann E., Wek, Ronald C., Spandau, Dan F |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567905/ https://www.ncbi.nlm.nih.gov/pubmed/25950825 http://dx.doi.org/10.1038/jid.2015.177 |
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