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T-bet and interleukin-27: possible T(H)1 immunomodulators of sarcoidosis
BACKGROUND: Sarcoidosis has often been termed an “immune paradox” as there is peripheral anergy to common recall antigens despite pronounced T(H)1-dominant inflammation at disease sites, such as the lung, with up-regulation of interferon γ, IL-27 and transcription factors. Peripheral blood may refle...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Basel
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568011/ https://www.ncbi.nlm.nih.gov/pubmed/26254778 http://dx.doi.org/10.1007/s10787-015-0247-y |