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Toxic Markers of Matrine Determined Using (1)H-NMR-Based Metabolomics in Cultured Cells In Vitro and Rats In Vivo

Matrine is one of the main bioactive alkaloids of Sophora flavescens Aiton, which has been widely used to treat various diseases in China. These diseases include viral hepatitis, liver fibrosis, cardiac arrhythmia, skin diseases, and tumors. However, matrine is also the main toxic compound of this h...

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Detalles Bibliográficos
Autores principales: Li, Zhonghuang, Zheng, Liang, Shi, Jian, Zhang, Guiyu, Lu, Linlin, Zhu, Lijun, Zhang, Jiajie, Liu, Zhongqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568042/
https://www.ncbi.nlm.nih.gov/pubmed/26413125
http://dx.doi.org/10.1155/2015/598412