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Mechanisms of amyloid formation revealed by solution NMR
Amyloid fibrils are proteinaceous elongated aggregates involved in more than fifty human diseases. Recent advances in electron microscopy and solid state NMR have allowed the characterization of fibril structures to different extents of refinement. However, structural details about the mechanism of...
Autores principales: | Karamanos, Theodoros K., Kalverda, Arnout P., Thompson, Gary S., Radford, Sheena E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568309/ https://www.ncbi.nlm.nih.gov/pubmed/26282197 http://dx.doi.org/10.1016/j.pnmrs.2015.05.002 |
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