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Posterior Cingulate Lactate as a Metabolic Biomarker in Amnestic Mild Cognitive Impairment
Mitochondrial dysfunction represents a central factor within the pathogenesis of the Alzheimer's disease (AD) spectrum. We hypothesized that in vivo measurements of lactate (lac), a by-product of glycolysis, would correlate with functional impairment and measures of brain health in a cohort of...
Autores principales: | Weaver, Kurt E., Richards, Todd L., Logsdon, Rebecca G., McGough, Ellen L., Minoshima, Satoshi, Aylward, Elizabeth H., Kleinhans, Natalia M., Grabowski, Thomas J., McCurry, Susan M., Teri, Linda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568343/ https://www.ncbi.nlm.nih.gov/pubmed/26417597 http://dx.doi.org/10.1155/2015/610605 |
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