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Mutations Found in embCAB, embR, and ubiA Genes of Ethambutol-Sensitive and -Resistant Mycobacterium tuberculosis Clinical Isolates from China

To better understand the molecular mechanisms of Ethambutol (EMB) resistance, the mutant hot spot region of five genes (embB, embA, embC, embR, and ubiA) was amplified and sequenced in 109 EMB-resistant and 153 EMB-susceptible clinical isolates from China. Twenty-seven EMB-susceptible isolates were...

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Detalles Bibliográficos
Autores principales: Xu, Yuhui, Jia, Hongyan, Huang, Hairong, Sun, Zhaogang, Zhang, Zongde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568347/
https://www.ncbi.nlm.nih.gov/pubmed/26417605
http://dx.doi.org/10.1155/2015/951706