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Kinematic, Dynamic, and Energy Characteristics of Diastolic Flow in the Left Ventricle

Blood flow characteristics in the normal left ventricle are studied by using the magnetic resonance imaging, the Navier-Stokes equations, and the work-energy equation. Vortices produced during the mitral valve opening and closing are modeled in a two-dimensional analysis and correlated with temporal...

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Autores principales: Khalafvand, Seyed Saeid, Hung, Tin-Kan, Ng, Eddie Yin-Kwee, Zhong, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568350/
https://www.ncbi.nlm.nih.gov/pubmed/26417381
http://dx.doi.org/10.1155/2015/701945
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author Khalafvand, Seyed Saeid
Hung, Tin-Kan
Ng, Eddie Yin-Kwee
Zhong, Liang
author_facet Khalafvand, Seyed Saeid
Hung, Tin-Kan
Ng, Eddie Yin-Kwee
Zhong, Liang
author_sort Khalafvand, Seyed Saeid
collection PubMed
description Blood flow characteristics in the normal left ventricle are studied by using the magnetic resonance imaging, the Navier-Stokes equations, and the work-energy equation. Vortices produced during the mitral valve opening and closing are modeled in a two-dimensional analysis and correlated with temporal variations of the Reynolds number and pressure drop. Low shear stress and net pressures on the mitral valve are obtained for flow acceleration and deceleration. Bernoulli energy flux delivered to blood from ventricular dilation is practically balanced by the energy influx and the rate change of kinetic energy in the ventricle. The rates of work done by shear and energy dissipation are small. The dynamic and energy characteristics of the 2D results are comparable to those of a 3D model.
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spelling pubmed-45683502015-09-28 Kinematic, Dynamic, and Energy Characteristics of Diastolic Flow in the Left Ventricle Khalafvand, Seyed Saeid Hung, Tin-Kan Ng, Eddie Yin-Kwee Zhong, Liang Comput Math Methods Med Research Article Blood flow characteristics in the normal left ventricle are studied by using the magnetic resonance imaging, the Navier-Stokes equations, and the work-energy equation. Vortices produced during the mitral valve opening and closing are modeled in a two-dimensional analysis and correlated with temporal variations of the Reynolds number and pressure drop. Low shear stress and net pressures on the mitral valve are obtained for flow acceleration and deceleration. Bernoulli energy flux delivered to blood from ventricular dilation is practically balanced by the energy influx and the rate change of kinetic energy in the ventricle. The rates of work done by shear and energy dissipation are small. The dynamic and energy characteristics of the 2D results are comparable to those of a 3D model. Hindawi Publishing Corporation 2015 2015-08-31 /pmc/articles/PMC4568350/ /pubmed/26417381 http://dx.doi.org/10.1155/2015/701945 Text en Copyright © 2015 Seyed Saeid Khalafvand et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Khalafvand, Seyed Saeid
Hung, Tin-Kan
Ng, Eddie Yin-Kwee
Zhong, Liang
Kinematic, Dynamic, and Energy Characteristics of Diastolic Flow in the Left Ventricle
title Kinematic, Dynamic, and Energy Characteristics of Diastolic Flow in the Left Ventricle
title_full Kinematic, Dynamic, and Energy Characteristics of Diastolic Flow in the Left Ventricle
title_fullStr Kinematic, Dynamic, and Energy Characteristics of Diastolic Flow in the Left Ventricle
title_full_unstemmed Kinematic, Dynamic, and Energy Characteristics of Diastolic Flow in the Left Ventricle
title_short Kinematic, Dynamic, and Energy Characteristics of Diastolic Flow in the Left Ventricle
title_sort kinematic, dynamic, and energy characteristics of diastolic flow in the left ventricle
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568350/
https://www.ncbi.nlm.nih.gov/pubmed/26417381
http://dx.doi.org/10.1155/2015/701945
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