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The role of mRNA and protein stability in the function of coupled positive and negative feedback systems in eukaryotic cells

Oscillators and switches are important elements of regulation in biological systems. These are composed of coupling negative feedback loops, which cause oscillations when delayed, and positive feedback loops, which lead to memory formation. Here, we examine the behavior of a coupled feedback system,...

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Detalles Bibliográficos
Autores principales: Moss Bendtsen, Kristian, Jensen, Mogens H., Krishna, Sandeep, Semsey, Szabolcs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568459/
https://www.ncbi.nlm.nih.gov/pubmed/26365394
http://dx.doi.org/10.1038/srep13910