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Cardiac Na(v)1.5 is modulated by ubiquitin protein ligase E3 component n-recognin UBR3 and 6
The voltage-gated Na(+) channel Na(v)1.5 is essential for action potential (AP) formation and electrophysiological homoeostasis in the heart. The ubiquitin–proteasome system (UPS) is a major degradative system for intracellular proteins including ion channels. The ubiquitin protein ligase E3 compone...
Autores principales: | Zhao, Chunxia, Wang, Lijie, Ma, Xiue, Zhu, Weidong, Yao, Lei, Cui, Yingyu, Liu, Yi, Li, Jun, Liang, Xingqun, Sun, Yunfu, Li, Li, Chen, Yi-Han |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568919/ https://www.ncbi.nlm.nih.gov/pubmed/26059563 http://dx.doi.org/10.1111/jcmm.12588 |
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