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Astaxanthin prevents pulmonary fibrosis by promoting myofibroblast apoptosis dependent on Drp1-mediated mitochondrial fission
Promotion of myofibroblast apoptosis is a potential therapeutic strategy for pulmonary fibrosis. This study investigated the antifibrotic effect of astaxanthin on the promotion of myofibroblast apoptosis based on dynamin-related protein-1 (Drp1)-mediated mitochondrial fission in vivo and in vitro. R...
Autores principales: | Zhang, Jinjin, Xu, Pan, Wang, Youlei, Wang, Meirong, Li, Hongbo, Lin, Shengcui, Mao, Cuiping, Wang, Bingsi, Song, Xiaodong, Lv, Changjun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568926/ https://www.ncbi.nlm.nih.gov/pubmed/26119034 http://dx.doi.org/10.1111/jcmm.12609 |
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